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Primary pancreatic tumors are rare in dogs and cats. Exocrine tumors include adenomas and adenocarcinomas, and endocrine tumors include insulinomas, gastrinomas, and glucagonomas. Insulinomas are the most common type of pancreatic tumor, followed by adenocarcinomas. Both tumors are more common in dogs than cats. Large breed dogs and Siamese cats may be predisposed. Insulinomas are usually diagnosed with the finding of hypoglycemia with normal to high insulin on bloodwork and concomitant clinical signs. Adenocarcinomas typically go undetected until the clinical signs of metastasis are evident. For both tumors, diagnostic imaging and exploratory surgery with tumor removal (or biopsy) and histopathology are needed for a definitive diagnosis. Insulinomas can be treated with surgery and chemotherapy. Surgery is possible with adenocarcinomas, but as the cancer is more diffuse and has usually metastasized by the time of diagnosis, the prognosis is poorer. Chemotherapy and radiation therapy are ineffective in the treatment of adenocarcinomas. Given the high rate of metastasis with these tumors, staging is recommended prior to surgery.
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The pancreas is a vital organ on the right side of the abdomen adjacent to the stomach. It produces enzymes to assist in food digestion and hormones such as insulin, which regulates blood sugar or glucose metabolism. When the pancreas becomes inflamed, the condition is called pancreatitis. Common clinical signs include decreased appetite, nausea, vomiting, lethargy, diarrhea, and abdominal pain. If the attack is severe, acute shock or death may occur. Successful pancreatitis management will depend on early diagnosis and prompt medical therapy.
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Pancreas-specific lipase is a form of lipase produced only in the pancreas and is highly specific to the pancreas. Blood values increase only when there is pancreatic inflammation. There is now a version of the fPLI test that can be used in-clinic (SNAP fPL© from IDEXX). Ideally, the sample should also be sent to the laboratory to get an actual value of fPLI to help with treatment and monitoring.
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The pancreas is a vital organ that produces enzymes to assist in food digestion and hormones such as insulin, which regulates blood sugar or glucose metabolism. Pancreatitis is inflammation of the pancreas. Common clinical signs include decreased appetite, nausea, vomiting, lethargy, diarrhea, and abdominal pain. Diagnosis is generally made with laboratory testing and/or abdominal ultrasound. Successful pancreatitis management will depend on early diagnosis and prompt medical therapy. The prognosis depends on the severity of the disease and the response to initial therapy.
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Pancreas-specific lipase is a form of lipase produced only in the pancreas and is highly specific to the pancreas. Blood values increase only when there is pancreatic inflammation. A version of the cPLI test can now be used in-clinic (SNAP fPL© from IDEXX). Ideally, the sample should also be sent to the laboratory to get an actual value of cPLI to help with treatment and monitoring.
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Pancrelipase is given by mouth and is used on and off label to treat exocrine pancreatic enzyme deficiency in dogs, cats, and birds. It is also used to treat fur balls in rabbits. Give as directed by your veterinarian. Common side effects at higher doses include diarrhea, cramping, gas, or vomiting. Do not use in pets that are allergic to pork. If a negative reaction occurs, please call your veterinary office.
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Pandora syndrome affects multiple organ systems, including the urinary tract. The term is often used synonymously with Feline Idiopathic Cystitis (FIC), but FIC is only one component of Pandora syndrome. It is believed to be related to chronic stress. This article discusses causes, signs, diagnosis, treatment, and prognosis for cats with this condition.
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Panniculitis is a localized inflammation of the tissues under the skin, causing a firm swelling (nodule) that may ulcerate and drain fluid. It is a common problem in cats and is less common in dogs. There are several causes of panniculitis, but in younger animals with a single lump, the cause is often blunt trauma and, in cats, it is often caused by bite wounds from fighting. An accurate diagnosis relies on the microscopic examination of tissue and the most common treatment is the surgical removal of the lump(s).
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Chronic superficial keratitis (CSK), or pannus, is a potentially blinding disease affecting the cornea. Any dog breed can be affected by pannus, but it is predominantly seen in German shepherds, Belgian shepherds, and border collies. Diagnosis is based on medical history and clinical signs. Treatment involves using topical corticosteroids or other immune-modulating drugs. If diagnosed early and treatment plans are followed, many dogs can have a good prognosis and live a normal life.
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Panosteitis is a painful inflammation of the outer surface or shaft of one or more long bones of the legs. It is sometimes called growing pains. Panosteitis is a condition that affects young, rapidly growing dogs. Panosteitis will be suspected if the patient shows pain when pressure is applied to the affected bone(s). The diagnosis is confirmed by X-rays, which usually show a characteristic increase in the density of the affected bones. Although this disease will spontaneously resolve, during episodes of lameness the condition is very painful. At these times, treatment is supportive, using pain medication and anti-inflammatory drugs as needed.
